What’s the affiliation between food regimen of lactating moms and breast milk oxidant-antioxidant standing?

In a latest examine revealed within the Worldwide Breastfeeding Journal, researchers assessed the affiliation between maternal food regimen and the oxidant-antioxidant standing in breast milk.

Research: The affiliation of maternal dietary high quality and the antioxidant-proxidant steadiness of human milk. Picture Credit score: Da Antipina/Shutterstock


The composition of human milk varies with time inside a lactating mom and between breastfeeding moms based mostly on a number of components such because the moms’ well being standing, dietary patterns, and vitamin. Enough vitamin throughout being pregnant and lactation is crucial to enhance maternal and toddler well being and may enhance the oxidant-antioxidant standing of breast milk.

Concerning the examine

Within the current survey-based cross-sectional examine, researchers evaluated the influence of improved maternal vitamin on the antioxidant-proxidant steadiness of human milk.

Lactating moms (n=350) aged between 20 years and 35 years with infants aged between one month and 6 months have been recruited between January and February 2021 from 4 healthcare facilities located in Iran, Birjand, and southern elements of Khorasan. Moms with acute or persistent well being problems have been excluded from the evaluation.

Breast milk samples have been obtained between 7:00 am and 10:00 am. The maternal dietary patterns have been assessed with the assistance of meals frequency questionnaires that included 65 objects. The antioxidant-proxidant standing of breast milk was evaluated by 2, 2′-diphenyl-1-picrylhydrazyl (DPPH), ferric decreasing antioxidant energy (FRAP), thiobarbituric acid reactive substances (TBARs), and Ellman assays.

As well as, the degrees of triglycerides, whole protein, and calcium have been measured, and demographic, psychological, and anthropometric knowledge have been obtained from the members The dietary sample scores have been used to categorize members into T1, T2 and T3 tertiles that denoted low, reasonable and excessive adherence to dietary patterns, respectively.

Multinomial and multivariate logistic regression modeling was used with knowledge changes for maternal age, power/caloric consumption, physique mass index (BMI), and intercourse of the toddler, principal part evaluation (PCA) was carried out and the adjusted odds ratios (OR) have been calculated.


Predominantly, two food regimen patterns have been recognized and categorized as wholesome (n=181 moms) or unhealthy (n=169) patterns. The wholesome dietary sample was characterised by larger consumption of entire grains, refined grains, legumes, non-green greens, eggs, and crimson meat. The unhealthy dietary sample was characterised by larger consumption of carbonated drinks, honey, snacks, rooster, and seafood.

The imply age of lactating moms was 30 years. The degrees of thiol (81 μmol/L versus 74 μmol/L) and DPPH (347 μmol/L versus 321 μmol/L) have been larger within the breast milk of T3 lactating moms consuming wholesome diets compared to T1 moms consuming wholesome diets. Thiol (74 μmol/L versus 79 μmol/L) and calcium (calcium 8.8 mg/dL versus 9.2 mg/dL) ranges in breast milk have been considerably lesser in T3 lactating moms consuming unhealthy diets compared to T1 moms consuming unhealthy diets.

No important affiliation was discovered between the socioeconomic and demographic traits of the members within the three tertiles of dietary patterns comprising maternal age, systolic blood stress (SBP), supply kind, BMI, demise of fogeys, divorce of fogeys, degree of mother or father training, and age, intercourse and listen to circumference of the infants.

Logistic regression modeling confirmed that consumption of wholesome meals by lactating moms was related to larger thiol (OR=1.2) and DPPH ranges (OR=1.3) in breast milk in T3 versus T1, whereas maternal adherence to unhealthy diets correlated with decrease milk thiol ranges (OR=1.3) and calcium ranges (OR=1.3) in T3 versus T1.

The dietary patterns of lactating moms can have an effect on the macronutrient composition of breast milk and lay a robust basis for the improved well being of the toddler. The antioxidant standing of breast milk relies on the composition of nutritional vitamins (A, C and E), enzymes (superoxide dismutase, glutathione peroxidase), and metals (zinc, selenium and copper) that may neutralize free radicals.

Vegetables and fruit are wealthy in antioxidants corresponding to phytonutrients and polyphenols, respectively, and are important for preserving mobile homeostasis. Meals corresponding to meat, milk, legumes, eggs, and fish meet the maternal necessities of magnesium, zinc, iron, calcium, and copper. Calcium is crucial for toddler progress, muscle contraction, formation of bones, coagulation of blood, and nerve conduction.


Total, the examine findings confirmed that maternal adherence to wholesome diets enriched with fruits, inexperienced greens, and different greens was related to improved oxidant-antioxidant steadiness in breast milk. Important variations have been present in DPPH, calcium, and thiol ranges amongst moms with wholesome and unhealthy dietary patterns.

The authors imagine that the current examine is the primary of its sort to find out the affiliation between maternal dietary patterns and breast milk content material performed on lactating moms. The childish antioxidant standing strongly is determined by the maternal antioxidant standing throughout being pregnant and continues to be preserved post-delivery by endogenous biomolecule manufacturing by the toddler based mostly on the exogenous biomolecule transmission by way of breast milk.

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